Anti-CD223 Antibody

CD223, also known as LAG-3 (Lymphocyte Activation Gene-3), is an immune checkpoint receptor expressed on activated CD4+ and CD8+ T lymphocytes, regulatory T cells, and natural killer cells. This polyclonal reagent from Antibodies.com is raised in rabbit against the human CD223 target and supplied as an unconjugated preparation in a 100 µl volume, supporting western blot analysis and ELISA detection of native or recombinant LAG-3 in cell lysates and purified protein samples.

Because the antibody recognizes multiple epitopes on the LAG-3 extracellular and cytoplasmic regions, it is useful for characterizing expression changes during T-cell activation, exhaustion, and immune regulation studies, including tumor-infiltrating lymphocyte research and checkpoint blockade investigations. The unconjugated format offers flexibility in secondary antibody pairing for immunoblotting workflows and downstream detection chemistries. The product is intended for research use only.

For handling, refrigerate upon receipt, protect from light, and minimize freeze-thaw cycles by aliquoting on first use to preserve antibody activity across multiple experiments.