Anti-CD206 Antibody

This rabbit polyclonal antibody from Antibodies.com targets CD206 (mannose receptor, MRC1), a 175 kDa C-type lectin surface protein that serves as a defining marker of M2-polarized, alternatively activated macrophages in human immune cell research. Supplied as 100 µl of unconjugated antisera, the reagent supports western blot analysis of CD206 in macrophage and dendritic cell lysates and is validated for ELISA against the human target. Common research applications include profiling tumor-associated macrophage infiltration in cancer tissue samples, tracking monocyte-to-macrophage differentiation in cell culture, and characterizing macrophage phenotypes in fibrosis, wound healing, and chronic inflammatory disease models. For western blot, the antibody pairs readily with HRP-conjugated anti-rabbit secondary reagents for chemiluminescent detection. To preserve activity, aliquot the vial upon first thaw to limit freeze-thaw cycles and store at -20°C; short-term working dilutions may be kept refrigerated. The unconjugated format gives laboratories flexibility to label with biotin, HRP, or a fluorophore of choice for downstream detection in flow cytometry, immunohistochemistry, or standard blotting workflows.