Anti-CD200 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com binds the human CD200 glycoprotein (also known as OX-2), a type-I transmembrane immunoregulator that engages the CD200 receptor on myeloid cells to deliver an inhibitory signal and dampen inflammatory responses. CD200 is broadly distributed across thymocytes, B lymphocytes, endothelial cells, neurons, and several tumor types, where overexpression has been associated with immune evasion in chronic lymphocytic leukemia, multiple myeloma, and solid tumor settings. The reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit, unconjugated, and validated for western blot and ELISA detection of the human target. Researchers working on tumor immune escape, microglial quiescence, or transplantation tolerance models apply this reagent to characterize CD200 expression patterns and downstream CD200R signaling. Each vial is ready for dilution into standard immunoblotting or plate-based immunoassay buffers and is intended for research use only.