Anti-CD20 Antibody

Rabbit polyclonal antibody targeting the human CD20 antigen, also designated MS4A1, a 33-37 kDa transmembrane phosphoprotein expressed on the surface of B-lymphocytes from the pre-B cell stage through mature B-cell development. This unconjugated reagent is supplied by Antibodies.com as a 100 µl volume and is validated for western blot and ELISA workflows in research settings. CD20 serves as a defining lineage marker for B-cell studies and is widely investigated in research on non-Hodgkin lymphoma, chronic lymphocytic leukemia, and the mechanism of action of therapeutic anti-CD20 monoclonal antibodies such as rituximab, including studies of antigen loss and antibody-drug conjugate development. The antibody is raised in rabbit, exhibits polyclonal reactivity against the human target, and is suitable for characterization of B-cell populations in lymphoma biopsy lysates, lymphoid cell line panels, and in vitro models of B-cell receptor signaling.