Anti-CD1E Antibody

A rabbit polyclonal reagent from Antibodies.com raised against the CD1E glycoprotein, this unconjugated primary antibody targets a CD1 family antigen-presenting molecule whose distinctive intracellular role in lipid antigen processing on dendritic cells and other professional antigen-presenting cells makes it a useful marker for immunology research.

Supplied as 100 µl of antibody at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, the reagent is validated for western blot and immunocytochemistry workflows, with reactivity confirmed against human, mouse, and rat CD1E to enable comparative studies across species.

Unlike its CD1A, CD1B, CD1C, and CD1D relatives, which present lipid antigens directly at the cell surface, CD1E primarily assists the loading of self and microbial lipids onto those other CD1 isoforms within endosomal and lysosomal compartments, so researchers use this antibody to investigate lipid antigen presentation, T cell biology, and mycobacterial immune recognition.

For best results, store the vial at -20°C in working aliquots, refrigerate at 4°C for short-term use, and limit freeze-thaw cycles to preserve antibody performance across repeated experiments.