Anti-CD180 Antibody

CD180, also designated RP105, is a Toll-like receptor family member displayed on the surface of mature B lymphocytes, where it associates with the MD-1 accessory protein to modulate recognition of bacterial lipopolysaccharide and downstream B cell activation. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against the human CD180 target and is validated for western blot detection in human cell and tissue lysates. The antibody is supplied as a 50 µl liquid preparation of rabbit IgG, sufficient for multiple blotting runs at standard working dilutions. Investigators working on B cell development, innate immune signaling, or TLR4-adjacent pathways can apply it as a primary detection reagent in standard western blot workflows. For storage, keep the vial refrigerated at 4°C and protect from light; aliquot on first thaw to limit freeze-thaw cycles and preserve activity across repeated experiments. Because the reagent is polyclonal, it recognizes multiple epitopes across the CD180 extracellular domain, increasing the chance of robust signal across different sample preparations.