Anti-CD180 Antibody

CD180, also known as RP105, is a 105 kDa type I transmembrane protein expressed primarily on B lymphocytes where it forms a heterodimeric complex with MD-1 on the cell surface. Antibodies.com provides a Rabbit polyclonal antibody targeting this protein, supplied as a 100 µl unconjugated reagent validated for Western blot and ELISA applications across Human, Mouse, and Rat samples. The polyclonal format enables recognition of multiple epitopes within the CD180 extracellular leucine-rich repeat domain, supporting studies of B-cell signaling, innate immune recognition of bacterial lipopolysaccharide, and lymphoid tissue homeostasis. Researchers commonly use this reagent to distinguish mature B-cell subsets and to investigate altered expression patterns observed in chronic lymphocytic leukemia and autoimmune models.