Anti-CD163b Antibody

A member of the scavenger receptor cysteine-rich (SRCR) superfamily, CD163b is a cell-surface hemoglobin-haptoglobin binding protein expressed predominantly on monocytes and macrophages, where it contributes to the clearance of hemoglobin released during erythrocyte turnover. This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes the human CD163b target and is supplied as a 100 µl aliquot for use in Western blot and ELISA workflows.

Because the antibody is provided without a fluorophore or enzyme label, it can be paired with secondary detection systems of the researcher's choice and adapted to immunoprecipitation, immunohistochemistry on fixed sections, and standard immunoblotting of whole-cell lysates or tissue homogenates. Its human reactivity makes it a useful tool for investigations of macrophage polarization, iron homeostasis, and the inflammatory signaling pathways that recruit or activate tissue-resident macrophages in cardiovascular, hepatic, and neuroinflammatory research models.