Anti-CD148 Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes human CD148, also designated DEP-1 or PTPRJ, a receptor-type protein tyrosine phosphatase broadly expressed across hematopoietic lineages and present on many epithelial cell types. The antibody is raised in Rabbit, purified as a polyclonal preparation, and supplied at 100 µl per vial. It has been validated for Western blot and ELISA workflows, making it a research-grade primary detection reagent for protein-level studies of CD148 in human samples. CD148 functions as a negative regulator of signaling downstream of receptor tyrosine kinases and lymphocyte activation pathways, and is implicated in immune cell function, contact inhibition, and tumor-suppressor biology. Researchers studying T-cell receptor modulation, leukocyte signaling, or the phosphatase's role in epithelial-mesenchymal contexts can use this reagent in standard immunoblotting and immunoassay formats. The unconjugated format allows flexible pairing with HRP, biotin, or fluorophore-labeled secondary reagents according to the chosen assay design. Storage recommendations: aliquot upon arrival to limit freeze-thaw cycles, store refrigerated short term and frozen long term, and protect from light when working with downstream fluorescent conjugates.