Anti-CD14 Antibody

Produced by Antibodies.com, this rabbit polyclonal IgG antibody specifically recognizes human CD14, a glycosylphosphatidylinositol-anchored surface receptor expressed predominantly on circulating monocytes and tissue macrophages. CD14 serves as a critical co-receptor for bacterial lipopolysaccharide detection, partnering with TLR4 and MD-2 to initiate innate immune signaling in response to gram-negative bacteria, making it a widely studied marker in sepsis research, monocyte activation studies, and macrophage biology. The reagent is supplied as a liquid preparation at 100 µg per vial, unconjugated for flexibility in downstream assay development. It is validated for western blot analysis of human cell lysates and primary monocyte-derived samples. For optimal antibody stability and binding performance, store the vial refrigerated and aliquot upon receipt to minimize freeze-thaw cycles.