Anti-CD11B (L1) Antibody

This unconjugated mouse monoclonal reagent from Antibodies.com recognizes CD11B, the integrin alpha-M (ITGAM) subunit that pairs with CD18 to form the Mac-1 complement receptor (CR3). Expressed on monocytes, macrophages, neutrophils, NK cells, and granulocytes, CD11B is widely used as a lineage marker in immunological and neuroinflammation research, where it is followed in studies of phagocytosis, leukocyte adhesion, and microglial activation. The antibody was raised against the L1 epitope and is supplied as 100 µl of purified protein in 0.1 M Tris-Glycine (pH 7.4) containing 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, with the azide acting as a preservative for short-term handling at 4 °C and the glycerol supporting frozen storage down to -20 °C without loss of titer. The recommended application is Western blot on lysates derived from human, mouse, and rat samples, taking advantage of the clone's cross-species reactivity. Because the product is unconjugated, laboratories can pair it with their own HRP, biotin, or fluorophore labels for downstream detection in cell biology and immunology workflows. The reagent is offered within the Antibodies.com catalogue as a primary antibody for researchers who need a reliable, conjugation-ready tool for tracking myeloid cell populations.