Anti-CCR7 Antibody

Raised in rabbits as a polyclonal IgG reagent, this Antibodies.com antibody targets the C-C chemokine receptor type 7 (CCR7), a seven-transmembrane G protein-coupled receptor that binds the homeostatic chemokines CCL19 and CCL21 and directs lymphocyte and dendritic cell trafficking toward secondary lymphoid tissues. The unconjugated format ships as a 200 µl liquid aliquot, giving laboratories the flexibility to pair it with their own HRP, fluorophore, or biotin-based secondary detection chemistry for western blot workflows. The antibody has been validated for WB on samples from human, mouse, and rat origins, supporting cross-species comparative studies of naive and central memory T cell phenotypes, germinal center B-cell subset characterization, and dendritic cell homing assays. Its reactivity across three commonly used model organisms also makes it practical for translational pipelines that move between murine disease models and human clinical specimens, including examinations of CCR7 upregulation reported in metastatic tumor microenvironments. Polyclonal specificity against multiple epitopes of the receptor helps maintain signal consistency where post-translational modifications or splice variants are of interest, and the unconjugated formulation allows direct conjugation in-house for custom multiplex panels.