Anti-CCR6 Antibody

This polyclonal reagent from Antibodies.com targets CCR6, a seven-transmembrane G protein-coupled receptor that directs cell migration toward its ligand CCL20 (MIP-3α) and serves as a defining surface marker on IL-17-producing helper T cells, certain regulatory B cell subsets, and specific dendritic cell populations. The antibody was raised in rabbit and is supplied as an unconjugated 100 µL liquid aliquot, ready for dilution into standard immunodetection buffers. Validated uses include Western blot analysis of CCR6 expression in cell lysates and immunohistochemistry on human tissue sections, supporting studies of mucosal inflammation, psoriatic skin lesions, inflammatory bowel disease biopsies, and lymphoid organ architecture. Investigators focused on Th17 trafficking, gut-homing lymphocyte biology, or tumor microenvironment immune infiltrates commonly apply anti-CCR6 antibodies to map receptor distribution at the protein level across these research settings.