Anti-CCP2 Antibody

For investigating citrullinated peptide recognition in autoimmune and inflammatory disease models, this rabbit polyclonal reagent from Antibodies.com targets the cyclic citrullinated peptide (CCP2) epitope recognized by anti-citrullinated protein autoantibodies (ACPAs). The unconjugated antibody is supplied as a 100 µl volume and is validated for Western blot, immunohistochemistry, and ELISA workflows across human and mouse sample types. Researchers studying rheumatoid arthritis pathogenesis, synovial inflammation, or PAD enzyme-mediated citrullination use this reagent to detect citrullinated targets in cell lysates, tissue sections, and recombinant antigen preparations. The polyclonal format offers broader epitope coverage than monoclonal alternatives, making it useful for screening novel citrullinated antigens and mapping ACPA reactivity patterns in patient sera or experimental arthritis models.