Anti-CCNT2 Antibody

Investigate cyclin T2 with this unconjugated rabbit polyclonal reagent from Antibodies.com, supplied in a 100 µl volume. CCNT2 (Cyclin T2) operates as a regulatory partner of CDK9 within the positive transcription elongation factor b (P-TEFb) complex, where the kinase phosphorylates the C-terminal domain of RNA polymerase II to drive productive transcript elongation. Alternative splicing generates two principal isoforms, T2a and T2b, which differ in their N-terminal regions and support distinct differentiation programs in hematopoietic and muscle lineages. Researchers working on HIV-1 Tat transactivation, myogenesis, or neuronal development use this reagent in western blot and immunohistochemistry workflows to probe complex assembly and expression dynamics. The polyclonal host response yields recognition of multiple epitopes across the human CCNT2 sequence, providing robustness when target abundance is variable. For handling, refrigerate the vial between experimental sessions and aliquot to limit freeze-thaw cycles during routine immunoblotting.