Anti-CCND2 Antibody

From Antibodies.com, this affinity-purified polyclonal reagent targets CCND2 (also known as G1/S-specific cyclin-D2) and is supplied as a 50 µl volume at 1.0 mg/mL in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. The antibody was raised in a rabbit host against recombinant human CCND2 protein and validated for Western blot (WB) detection across human, mouse, and rat samples, making it useful for comparative cell-cycle studies of the G1/S transition. It is delivered unconjugated, leaving the end user free to pair it with their own HRP, fluorophore, or biotin detection chemistry, and is shipped at 4 °C; upon arrival it should be aliquoted and stored at –20 °C with repeated freeze/thaw cycles avoided to preserve binding activity. The reagent is reported to recognize the endogenous total pool of CCND2, supporting workflows that examine cyclin D2 partnering with CDK4/CDK6 and downstream Rb phosphorylation. As a polyclonal preparation, it offers multi-epitope recognition that can be advantageous for immunoblotting where signal amplification is desired, and its broad human/mouse/rat reactivity profile suits translational research programs that need consistent reagent performance across model systems and patient-derived material.