Anti-CCND1 (phospho T286) Antibody

Raised in rabbit, this polyclonal IgG antibody from Antibodies.com recognizes human cyclin D1 only when threonine 286 is phosphorylated, the GSK3β-mediated modification that drives nuclear export and ubiquitin-dependent turnover of this key G1/S cell-cycle regulator. Supplied as 50 µl of unconjugated reagent for western blot workflows, the antibody is validated on human samples and reveals the endogenous phospho-T286 band without needing a secondary label. Investigators studying oncogenic cyclin D1 stabilization, mitogenic signaling, and DNA damage responses rely on this phospho-specificity to distinguish the active nuclear pool from the exported, degradation-marked cytoplasmic fraction of the protein.