Anti-CCNC Antibody

Cyclin C (CCNC) is a regulatory cyclin that partners with CDK8 and CDK19 to form the Mediator-associated kinase module, controlling RNA polymerase II-driven transcription and linking cell-cycle progression to stress response pathways. This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes human, mouse, and rat Cyclin C, and is validated for western blot and immunohistochemistry applications on routinely prepared lysates and tissue sections. The antibody is supplied in a single vial as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol, a cryoprotective buffer that allows storage at -20°C with minimal freeze-thaw damage when aliquoted. Because the polyclonal format recognizes multiple epitopes across the CCNC primary sequence, it is particularly useful for tracking endogenous protein expression in models of mitochondrial fission, oxidative stress signaling, and CDK8/CDK19-CycC complex assembly, where Cyclin C relocalization and turnover are increasingly studied.