Anti-CCNB1 Antibody

A polyclonal rabbit IgG reagent from Antibodies.com directed against CCNB1 (Cyclin B1), the cyclin family member that partners with CDK1 to form M-phase promoting factor and drive the G2/M transition during mitosis. The unconjugated antibody is supplied as a 100 µl liquid aliquot and is validated for western blot detection of the human target, supporting research on cell cycle progression, mitotic checkpoint control, and proliferative signaling in tumor biology. Because Cyclin B1 accumulates in late G2 and is degraded at the metaphase-to-anaphase transition, the reagent is widely used to monitor mitotic entry and exit, aneuploidy studies, and the cytotoxic response of candidate chemotherapeutics in cancer cell models. IgG isotype confirmation enables flexible pairing with secondary antibodies in standard immunoblotting workflows, and the documented human reactivity profile makes the reagent applicable to cell line-derived lysates commonly used in cell cycle, checkpoint, and proliferation research.