Anti-CCNA1 Antibody

CCNA1 (Cyclin A1) is a cell-cycle regulator that partners with CDK1 and CDK2 to drive the G2/M transition, with particularly prominent expression in meiotic germ cells of the testis. Antibodies.com supplies this unconjugated rabbit polyclonal antibody for the detection of human Cyclin A1 in Western blot (WB) and immunohistochemistry (IHC) workflows. In reproductive biology research, the antibody is used to map Cyclin A1 localization in spermatogonia, spermatocytes, and spermatids, supporting studies of meiotic progression and germ-line development. Cancer researchers also apply it to characterize CCNA1 expression in acute myeloid leukemia, where the gene is frequently overexpressed, and in other solid-tumour contexts where cell-cycle dysregulation is under investigation. Each preparation is provided in a 100 µl volume of polyclonal rabbit serum, unconjugated so that investigators can pair it with HRP, fluorescent, or biotin-based secondary reagents of their choice. The reagent is specific to the human Cyclin A1 target and should be stored refrigerated and protected from light to preserve binding activity across repeated freeze-thaw cycles of working aliquots.