Anti-CCM2 Antibody

CCM2 (Cerebral Cavernous Malformations 2) is a scaffold protein involved in vascular homeostasis, and detecting its endogenous expression in tissue and cell lysates requires a reagent with confirmed cross-reactivity across standard mammalian model systems.

This unconjugated polyclonal antibody from Antibodies.com is raised in rabbit and validated for Western blot and immunohistochemistry workflows, giving flexibility for both protein-level studies and tissue localization experiments. The reagent recognizes human, mouse, and rat CCM2, making it useful for comparative work across these species in cerebral cavernous malformation research and related signaling pathway investigations.

It is supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, allowing refrigerated storage and protection from light during routine handling. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which can be advantageous when studying CCM2 variants or partial degradation products in vascular biology research.