Anti-CCL17 Antibody

Sourced from the Antibodies.com primary antibody catalogue, this rabbit-derived reagent provides reliable detection of CCL17 (also known as TARC, thymus and activation-regulated chemokine), a CC-chemokine implicated in T-cell trafficking and thymic T-cell development. The antibody is raised in rabbits and is offered as a polyclonal, unconjugated IgG preparation — no fluorophore, biotin, or HRP is attached — making it well suited for laboratories that prefer to choose their own secondary labelling strategy. It is supplied at a working concentration of 1.0 mg/ml in a 50 µl aliquot, intended for research use only. Validated applications include Western Blot (WB) for protein-level detection and Immunohistochemistry (IHC) for tissue localisation studies, while the reagent has been confirmed to react with human samples, covering investigations into inflammatory skin conditions, allergic responses, and CCR4-mediated signalling pathways in which CCL17 participates. As a polyclonal reagent, the antibody recognises multiple epitopes across the CCL17 target, which generally improves sensitivity and tolerance to minor protein variations. The product is intended for research use only and should be stored frozen in single-use aliquots at –20 °C to preserve the 1.0 mg/ml stock, with brief bench use on ice; small working volumes may also be kept at 2–8 °C for short-term experiments, and repeated freeze–thaw cycles should be avoided. Researchers performing Western Blot can typically load 10–20 µg of total lysate per lane, whereas IHC working dilutions in the 1:100–1:500 range are commonly reported for comparable polyclonal anti-CCL17 preparations. For CCR4/CCL17 axis studies, paired use with appropriate secondary antibodies (anti-rabbit HRP or anti-rabbit fluorophore conjugates) is recommended to match the unconjugated format of this primary reagent.