Anti-CCL11 Antibody

The Antibodies.com rabbit polyclonal antibody targets CCL11 (also called eotaxin), a C-C motif chemokine central to eosinophil recruitment, allergic airway inflammation, and eosinophilic pathology in conditions such as asthma and atopic dermatitis. Raised in rabbit and supplied unconjugated at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide at approximately pH 7.2, this affinity-purified reagent is validated for Western blot detection of endogenous CCL11 protein in human, mouse, and rat samples.

Each vial contains 100 µl of antibody, providing enough material for multiple immunoblotting experiments when diluted to working concentrations. The polyclonal format presents epitope diversity, supporting recognition of multiple regions of the CCL11 chemokine and offering resilience against minor epitope modifications. Recommended storage includes refrigerated conditions to preserve antibody integrity; sodium azide is included as a microbial preservative, and aliquoting helps limit freeze-thaw exposure of the working solution.

CCL11 expression is extensively characterized in respiratory, dermatological, and neuroinflammatory research, where Western blot analysis clarifies chemokine signaling pathways, receptor interactions, and tissue distribution. The unconjugated format allows flexible pairing with HRP, alkaline phosphatase, or fluorescent secondary reporters, accommodating a broad choice of detection chemistries for immunoblotting workflows.