Anti-CCDC6 Antibody

Rabbit polyclonal IgG antibody raised against human CCDC6, supplied by Antibodies.com as a 200 µl liquid aliquot for Western blot applications. CCDC6 (Coiled-Coil Domain Containing 6) is a ~53 kDa nuclear protein best known for its role in the DNA damage response, where it interacts with DNA-PKcs and modulates ATM signaling, and as a tumor suppressor implicated in papillary thyroid carcinoma through the chromosome 10q21 rearrangement. Researchers studying apoptosis, checkpoint control, and oncogenic fusion proteins (including RET/PTC rearrangements) use anti-CCDC6 reagents to detect endogenous levels of the protein by Western blot in human cell lines and tissue lysates. The unconjugated format supports pairing with HRP- or fluorophore-labeled secondary antibodies for chemiluminescent or fluorescent Western blot workflows, and the polyclonal host background provides broader epitope coverage for detection of full-length and isoform variants. Short-term storage at 4 °C with longer term aliquoting at -20 °C preserves antibody activity across multiple freeze-thaw cycles.