Anti-CCDC6 Antibody

Produced as a rabbit polyclonal reagent and validated for Western blot detection of endogenous human CCDC6, this unconjugated IgG antibody is supplied by Antibodies.com as a 100 µL aliquot. CCDC6 (Coiled-Coil Domain Containing 6), also referred to in the literature as TST1 or D10S170, is a ubiquitously expressed coiled-coil protein that participates in the DNA damage response and acts as a tumor suppressor; it is best characterized as the N-terminal partner in the RET/PTC chimeric oncoprotein that drives a subset of papillary thyroid carcinomas.

Investigators working on thyroid oncogenesis, genomic instability, or ATM-ATR checkpoint signaling use this reagent to probe CCDC6 expression in cell lysates and tumor-derived samples, supporting applications such as signal-transduction research, cancer biology studies, and dissection of fusion-protein rearrangements. The antibody is provided as a liquid polyclonal IgG preparation in a single vial, intended for research use only and stored refrigerated between uses to preserve binding activity across multiple experiments.