Anti-CBX5 Antibody [Assigned #A10612]

This mouse monoclonal IgG antibody recognizes CBX5 (Chromobox protein homolog 5), widely known as Heterochromatin Protein 1 alpha (HP1α), a chromatin-associated reader of histone H3K9 methylation marks involved in heterochromatin maintenance, gene silencing, and telomere stability. Supplied by Antibodies.com as an unconjugated reagent in a 200 µl volume, the clone was raised against the CBX5 target and cross-reacts with the human, mouse, and rat orthologs. It is validated for Western blot and immunohistochemistry, supporting chromatin biology studies, nuclear architecture analyses, and DNA damage response research in both cell lysates and tissue sections. The unconjugated format lets investigators pair it with their preferred fluorescent or enzymatic secondary detection reagents, and the mouse IgG isotype is compatible with standard anti-mouse secondary systems. Intended for research use only, this antibody serves laboratories studying epigenetic regulation, HP1α-mediated chromatin compaction, and histone modification–dependent transcriptional control.