Anti-CBX5 Antibody [Assigned #A10612]

This unconjugated mouse monoclonal IgG antibody targets CBX5 (also called HP1α), a chromodomain-containing reader of histone H3 lysine 9 trimethylation that anchors heterochromatin. Supplied by Antibodies.com as 100 µl in a single-use vial, the clone is validated for Western blot (WB) and immunohistochemistry (IHC) on Human, Mouse, and Rat samples. Common applications include tracking pericentromeric heterochromatin localization, monitoring CBX5 recruitment to DNA double-strand break sites, and probing silencing of repetitive genomic elements during differentiation or senescence. The unconjugated IgG format supports downstream conjugation with fluorophores, biotin, or horseradish peroxidase for flexible detection. For best stability, aliquot the reagent upon arrival and store refrigerated, protecting from light and avoiding repeated freeze-thaw cycles. The antibody is intended for research use only in chromatin and epigenetics studies.