Anti-CBX5 Antibody

CBX5, also known as heterochromatin protein 1 alpha (HP1α), is a chromodomain-containing nuclear protein that recognizes trimethylated histone H3 lysine 9 (H3K9me3) and drives heterochromatin compaction, transcriptional silencing, and DNA damage response signaling. This unconjugated mouse monoclonal IgG2b reagent from Antibodies.com enables detection of endogenous CBX5 across four species – human, mouse, rat, and canine samples – by Western blot and immunocytochemistry, making it well suited to chromatin biology, epigenetics, and nuclear architecture studies. Supplied as 100 µl of liquid antibody, the reagent is intended for dilution into standard blotting and immunostaining buffers and supports work ranging from mapping HP1α recruitment to pericentromeric foci to tracking chromatin remodeling after genotoxic stress.