Anti-CBX5 Antibody

Generated in rabbit and offered by Antibodies.com, this polyclonal reagent targets CBX5 — the chromodomain-containing protein widely cited as HP1 alpha — which mediates heterochromatin assembly and reads the H3K9me3 histone mark. Each vial ships as 100 µL of unconjugated antisera, validated for western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation across human, mouse, and rat samples.

The reagent serves as a tool for laboratory research on epigenetic silencing, heterochromatin spreading, telomere maintenance, and the DNA damage response. Aliquot upon first thaw, store at -20°C, and limit freeze-thaw exposure; protect from light and avoid unnecessary time at room temperature. Each preparation from Antibodies.com is supplied for in vitro research use only and supports applications such as ChIP-seq enrichment profiling, subnuclear localization imaging, and co-immunoprecipitation of CBX5-containing complexes.