Anti-CBX4 Antibody

Chromobox 4 (CBX4) is a Polycomb group protein that functions as an E3 SUMO ligase and a reader of histone H3 lysine 27 trimethylation (H3K27me3), helping regulate transcription, chromatin compaction, and the DNA damage response. This rabbit polyclonal reagent from Antibodies.com targets the CBX4 protein and is validated for Western blot, immunohistochemistry, and immunoprecipitation workflows, supporting studies of stem cell maintenance, X-inactivation, and oncogenic signaling pathways. Supplied as 50 µl of unconjugated IgG, the antibody shows reactivity with human and mouse samples, enabling cross-species investigation in cancer biology, developmental research, and chromatin biology. Store refrigerated and protect from light to preserve activity, and aliquot if extended storage is needed to minimize freeze-thaw cycles. Pair with appropriate secondary reagents for chromogenic or fluorescence detection as required by each application.