Anti-CBR1 Antibody

CBR1 (carbonyl reductase 1) is a cytosolic NADPH-dependent oxidoreductase that reduces quinones, prostaglandins, steroid hormones, and anthracycline chemotherapeutics such as doxorubicin. This rabbit polyclonal reagent from Antibodies.com was raised against human CBR1 and recognizes the native protein in its unconjugated form, making it compatible with the secondary reporter system of the researcher's choice. Validated for Western blot and immunohistochemistry workflows on human samples, the antibody is supplied as a 100 µL liquid aliquot ready for dilution into standard blocking buffers. Investigators studying xenobiotic metabolism, oxidative carbonyl stress, or chemotherapy resistance pathways can use it to profile CBR1 expression across cell lines, tumor specimens, and matched normal controls. Short-term refrigerated storage preserves activity, while freezing in working aliquots helps limit freeze-thaw damage to the immunoglobulin preparation. The polyclonal format broadens epitope coverage, which is useful when probing truncated variants or post-translationally modified forms of the reductase encountered in tissue lysates. Researchers are encouraged to optimize primary antibody dilution empirically for each application, because fixed-tissue IHC and denaturing Western blots typically require different working concentrations. The reagent is intended for research use only and is not validated for diagnostic procedures.