Anti-CBL (phospho Y700) Antibody - Identical to Abcam (ab202127)

The Antibodies.com rabbit polyclonal IgG antibody specifically recognizes CBL (Casitas B-lineage lymphoma) only when phosphorylated at tyrosine 700, a regulatory site in the linker region that modulates E3 ubiquitin ligase activity and downstream receptor tyrosine kinase signaling. Supplied as 50 µl of unconjugated antiserum, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence on human samples, supporting studies of receptor downregulation, cytokine signaling, and oncogenic transformation pathways. Phospho-specific recognition allows researchers to distinguish active from inactive CBL pools in cell lysates and tissue sections, with the unconjugated format enabling flexible detection chemistry and signal amplification strategies tailored to each experimental workflow.