Anti-CAV1 (phospho Y14) Antibody - Identical to Abcam (ab194869)

Caveolin-1 phosphorylated at tyrosine 14 is a hallmark of active Src-family kinase signaling at membrane microdomains, and this rabbit polyclonal reagent from Antibodies.com is raised specifically against that phospho-epitope. Supplied as 50 µL of unconjugated IgG, it is validated for Western blot and immunofluorescence workflows on human, mouse, and rat samples, making it useful for tracking mechanotransduction, focal adhesion turnover, and caveolar endocytosis in primary cells and tissue sections.

Researchers studying cancer cell invasion, vascular remodeling, or fibrosis often pair this reagent with total CAV1 blots to determine the activation state of caveolar signaling, since the phospho-Y14 modification reflects engagement of caveolae in cell-matrix and growth-factor responses rather than steady-state expression. The polyclonal host background gives broader epitope coverage than a monoclonal, which is helpful when the phospho-Y14 mark is being monitored across multiple orthologs or under variable upstream kinase input.