Anti-cathepsin D Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets cathepsin D, a lysosomal aspartic protease widely studied in cancer biology, neurodegeneration, and lysosomal storage disorder models. Produced in rabbit hosts and supplied as an unconjugated reagent, it is validated for Western blot and immunohistochemistry workflows on human samples, supporting detection of both the mature heavy chain (~34 kDa) and the pro-cathepsin D precursor (~48 kDa) in whole-cell lysates and formalin-fixed tissue sections.

Packaged as a 100 µl liquid aliquot, the reagent is suited to probing endogenous cathepsin D expression in breast carcinoma and melanoma research, where elevated cathepsin D levels have been linked to proliferative and metastatic phenotypes, as well as to apoptosis and autophagy pathway studies. Storage at -20 °C in single-use working aliquots helps preserve binding activity across repeated freeze-thaw cycles, and the polyclonal format offers broader epitope coverage than monoclonal alternatives when working with denatured or partially processed forms of the target. For research use only.