Anti-Caspase 9 (G140) Antibody

Raised in rabbit against the initiator caspase that drives the mitochondrial (intrinsic) apoptosis pathway, this unconjugated polyclonal reagent is supplied by Antibodies.com as a 100 µl volume at 1 mg/ml in phosphate-buffered saline containing 15 mM sodium azide at approximately pH 7.2. The immunogen corresponds to a region surrounding residue G140 of human Caspase 9, allowing the antibody to recognize both the ~46 kDa full-length zymogen and the ~35 kDa cleaved large subunit that accumulates during apoptosis.

Validated for Western Blot, it cross-reacts with mouse and rat Caspase 9 in addition to the human protein, supporting comparative cell death studies across standard laboratory models. The host species is rabbit, the clonality is polyclonal, and the conjugate is unconjugated, so the reagent pairs with secondary antibodies of the researcher's choice, including HRP, fluorophore, or biotin conjugates.

Store refrigerated in the original vial and avoid repeated freeze-thaw cycles; for extended storage, aliquot the stock to minimize handling. Sodium azide is included as a preservative. Intended for research use only and not for diagnostic applications.