Anti-Caspase 9 Antibody

Caspase 9 is an initiator cysteine protease that sits at the top of the intrinsic (mitochondrial) apoptotic cascade, and this rabbit polyclonal primary antibody from Antibodies.com is raised against it for detection in research workflows. After cytochrome c release into the cytosol, caspase 9 is recruited into the Apaf-1 apoptosome, where it undergoes autocleavage and proceeds to activate downstream executioner caspases such as caspase 3 and caspase 7. Researchers apply the unconjugated reagent on western blots to resolve full-length procaspase 9 (~46 kDa) and its cleaved subunits, and on immunohistochemistry preparations to map caspase 9 distribution across Human, Mouse, and Rat tissue sections.

Shipped as 100 µl of polyclonal antiserum in a single vial, the antibody is supplied ready for short-term refrigerated storage; aliquot on first use to minimize freeze-thaw cycles and protect the reagent from light. Host species is Rabbit, clonality is Polyclonal, and the conjugate is Unconjugated, leaving the antibody compatible with a broad selection of HRP- or fluorophore-labeled secondary reagents. It is intended for research use only in apoptosis, cancer biology, and neurodegeneration studies that interrogate caspase 9 by western blot and immunohistochemistry.