Anti-caspase-4 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this antibody targets human caspase-4, an inflammatory cysteine protease that drives non-canonical inflammasome activation and pyroptosis in response to intracellular LPS. The unconjugated antiserum is supplied at 100 µl per vial and validated for western blot, immunohistochemistry, and immunofluorescence, supporting detection of endogenous caspase-4 in cell lysates, fixed tissue sections, and cultured cells. Researchers working on sepsis, endotoxemia, autoinflammatory disease, and innate immune signaling can pair it with HRP- or fluorophore-conjugated secondary antibodies for chromogenic or fluorescence readouts, while appropriate blocking and dilution buffers help preserve epitope recognition across platforms.