Anti-Caspase-3 Antibody

A rabbit-derived polyclonal reagent from Antibodies.com raised against the Caspase-3 effector protease, supplied as 100 µl of unconjugated antibody suitable for western blot and ELISA workflows. Caspase-3 is a central executioner caspase in the apoptotic cascade, and antibodies targeting it are routinely used to monitor both the inactive zymogen (~35 kDa) and its cleaved, catalytically active fragments that arise once apoptosis has been triggered.

Researchers in oncology, neurobiology, and developmental biology rely on this type of reagent to chart programmed cell death in response to drug treatment, oxidative stress, or developmental cues. The antibody has been validated for reactivity with Human and Monkey samples, giving it utility across translational studies that span primate-derived cell lines and primary tissue.

As a polyclonal reagent, the antibody recognizes multiple epitopes on the target, which can improve detection of processed forms that may otherwise be missed by epitope-masked monoclonals. Each aliquot is intended for research use only and pairs with standard HRP-based or fluorescent secondary detection systems depending on the assay format chosen.