Anti-Caspase 3 Antibody

Caspase 3 is a critical executioner protease in the apoptotic cascade, and this unconjugated rabbit polyclonal reagent from Antibodies.com enables detection of both the intact 35 kDa proenzyme and its active cleaved fragments. Supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples. Researchers investigating programmed cell death, neurodegeneration models, or chemotherapeutic response commonly apply it to monitor activation status through cleavage pattern shifts on blot membranes or changes in subcellular distribution in fixed tissue sections. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which can be advantageous when probing for processed forms that may have lost conformational determinants present in the full-length protein.