Anti-CASP9 Antibody

CASP9 encodes caspase-9, an initiator caspase central to the mitochondrial (intrinsic) apoptosis pathway, where it forms the apoptosome complex with Apaf-1 and cytochrome c to cleave and activate downstream effector caspases such as caspase-3. This unconjugated Rabbit polyclonal reagent from Antibodies.com is raised against CASP9 and validated for western blot and immunofluorescence workflows on Human and Mouse samples, supporting studies of programmed cell death, cancer biology, and neurodegeneration. Supplied as 100 µl of polyclonal antiserum in a vial, the antibody binds the endogenous CASP9 protein and detects full-length procaspase-9 alongside processed fragments generated during apoptotic signaling. For handling, refrigerate the antibody upon receipt and aliquot to limit freeze-thaw cycles, preserving activity across repeated western blot and IF experiments. Researchers investigating intrinsic apoptosis, drug-induced cell death, or developmental cell clearance use the reagent as a primary antibody in membrane probing and cell imaging workflows.