Anti-CASP3 Antibody [Assigned #A11024]

Antibodies.com offers this rabbit monoclonal reagent targeting Caspase-3 (CASP3), a cysteine-aspartic protease that serves as a central executioner of programmed cell death. The clone, designated by the manufacturer's internal reference A11024, is supplied as 200 µl of an unconjugated IgG formulation suitable for multiple immunodetection workflows.

Validated applications include western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), and immunoprecipitation (IP), with demonstrated reactivity against Human and Rat samples. Investigators typically use this reagent to monitor full-length procaspase-3 (~32-35 kDa) and the signature p17 and p12 cleavage fragments generated when apoptosis is activated, supporting work in cancer biology, neurodegeneration research, and toxicology studies.

For best results, aliquot the antibody upon arrival to limit freeze-thaw cycles and store at -20 °C in working volumes to preserve binding activity across repeated experiments. As an unconjugated primary reagent, it offers flexibility to pair with the user's preferred secondary antibodies for chemiluminescent, chromogenic, or fluorescence-based readouts.