Anti-CASP3 Antibody

Raised in rabbit against the caspase-3 executioner protease, this unconjugated polyclonal reagent from Antibodies.com supports apoptosis research across human, mouse, and rat model systems. The antibody recognizes full-length CASP3 as well as the cleaved p17 and p12 fragments that mark active enzyme, making it useful for tracking both zymogen expression and proteolytic processing during programmed cell death.

Validated for Western blot, immunofluorescence, and immunoprecipitation workflows, the reagent ships as a 100 µl liquid aliquot and pairs with standard HRP- or fluorophore-conjugated secondary antibodies. Investigators studying neurodegeneration, chemotherapy-induced tumor response, or developmental cell loss apply it to cultured mammalian cells, fixed tissue sections, and whole-cell lysates from rodent models to follow caspase activation kinetics. For ongoing bench use, keep refrigerated, protect from light, and prepare small working aliquots to limit freeze-thaw cycles and preserve antibody titer across multiple experiments.