Anti-CASC3 Antibody

CASC3 (Cancer Susceptibility 3), also known as MLN51, is a core component of the exon junction complex that deposits on spliced mRNAs and supports nuclear RNA export, translational control, and nonsense-mediated decay. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human CASC3 and validated for Western blot and immunohistochemistry workflows, where it enables detection of endogenous protein in cell lysates and fixed tissue sections. The antibody is supplied in 100 µl aliquots as a polyclonal antiserum suitable for probing both nuclear and cytoplasmic pools of CASC3, which has been linked to breast cancer susceptibility and alternative splicing regulation. Store refrigerated and avoid repeated freeze-thaw cycles to preserve reagent performance. For research use only in studies of RNA processing, splicing-coupled quality control, and tumor biology.