Anti-CARD14 Antibody

This rabbit polyclonal reagent targets CARD14 (Caspase Recruitment Domain Family Member 14), a membrane-associated scaffold protein that couples protein kinase C activation to NF-kB signaling in keratinocytes and other cell types. Distributed by Antibodies.com and raised in rabbit, the antibody is supplied unconjugated and validated for Western blot detection across human, mouse, and rat samples, making it useful for comparative studies of inflammatory skin signaling pathways.

CARD14 gain-of-function variants are linked to psoriasis susceptibility (PSORS2) and familial pityriasis rubra pilaris, so the reagent supports research into skin inflammation, epithelial immunity, and downstream IKK complex activation. The product is provided at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide, pH approximately 7.2, and ships as a 100 µl vial suitable for multiple immunoblot experiments.