Anti-CANT1 Antibody

CANT1 (Calcium Activated Nucleotidase 1) is a Golgi-resident UDP-sugar hydrolase whose catalytic activity depends on calcium ions. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human protein and validated for Western blot and immunofluorescence workflows on human samples. Supplied as 100 µl of ready-to-use antibody in a single vial, it supports detection of endogenous CANT1 in cell lysates and fixed-cell imaging preparations. For short-term use, store refrigerated at 4°C; for longer term, aliquot the reagent and freeze at -20°C to preserve activity across repeated freeze-thaw cycles. The polyclonal format offers broader epitope coverage than a monoclonal clone, an advantage for researchers probing glycosylation pathways, Desbuquois dysplasia models, or Golgi membrane biology. CANT1 hydrolyses UDP-sugars generated in the lumen of the Golgi, so this reagent is a useful marker for tracking Golgi-resident enzymes and the consequences of loss-of-function mutations linked to skeletal dysplasia. Intended for research use only, not for diagnostic or therapeutic applications.