Anti-CALU Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against calumenin (CALU), a member of the CREC family of EF-hand calcium-binding chaperones localized predominantly to the endoplasmic reticulum lumen. Validated for Western blot and immunofluorescence workflows, the antibody enables detection of endogenous CALU across human, mouse, and rat samples. Supplied as a 100 µl aliquot in a vial, the reagent supports readouts including the ~37 kDa calumenin band in cell and tissue lysates, along with visualization of ER-resident CALU in fixed-cell imaging. The rabbit host and polyclonal clonality allow broad epitope coverage for studies where CALU regulation matters, such as vitamin K-dependent gamma-carboxylation, ER stress responses, and reported roles in cardiac and bone biology. Researchers characterizing thrombotic pathways, where calumenin acts as an inhibitor of vitamin K epoxide reductase, can use this antibody for both protein-level expression analysis and subcellular localization.