Anti-Calmodulin Antibody

Calmodulin is a 17 kDa calcium-binding protein that acts as a universal intracellular calcium sensor, modulating the activity of kinases, phosphatases, ion channels, and metabolic enzymes across eukaryotic systems. This unconjugated rabbit polyclonal reagent from Antibodies.com targets endogenous calmodulin for detection across multiple experimental platforms, including Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows.

Validated on human, mouse, and rat samples, the antibody supports studies of calcium signaling, synaptic plasticity, cell cycle regulation, and smooth muscle contraction where calmodulin-dependent pathways are central. Researchers investigating neuronal calcium dynamics, cardiac contractility, or receptor-mediated signal transduction can apply the reagent to formalin-fixed paraffin-embedded sections for IHC, cultured cell monolayers for IF, or lysate preparations for immunoblotting.

The 100 µl format provides enough volume for multiple staining runs and titrations. The polyclonal nature of the reagent increases the likelihood of recognizing multiple epitopes on the calmodulin molecule, which is useful given the conserved sequence across mammalian species. Store refrigerated and protect from light to preserve antibody activity across repeated experiments.