Anti-Calcipressin-1 Antibody

Calcipressin-1, also known as RCAN1 or DSCR1, functions as an endogenous inhibitor of calcineurin-dependent signaling through the NFAT transcription factor pathway. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the Calcipressin-1 target and is validated for Western Blot detection in human, mouse, and rat samples.

The reagent is supplied as 100 µl of liquid at 1 mg/ml in PBS containing 0.1% Sodium Azide and 50% glycerol. The polyclonal format enables recognition of multiple epitopes on the target protein, which is useful when probing endogenous Calcipressin-1 expression across tissues where isoform variation or post-translational modification may occur.

Research applications for this antibody include studies of calcium and calcineurin signaling in cardiac hypertrophy, neuronal calcium dysregulation in Down syndrome and Alzheimer's disease models, oxidative stress responses, and immune cell regulation. Investigators examining RCAN1/DSCR1 function in vascular endothelial inflammation, mitochondrial signaling, or T-cell activation pathways use this reagent as a primary detection antibody in Western Blot workflows.