Anti-CALB2 Antibody

CALB2, also known as calretinin or calbindin-2, is a 29 kDa calcium-binding protein of the EF-hand family expressed in select neuronal populations, mesothelial cells, and adrenal cortex tissue. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against CALB2 and validated for Western blot and immunohistochemistry workflows. The antibody detects the human, mouse, and rat orthologs, supporting comparative studies that span rodent disease models and human tissue archives. Each vial contains 100 µL of polyclonal antiserum, supplied unconjugated so researchers can pair it with their preferred HRP, biotin, or fluorophore-conjugated secondary reagents. In research and pathology laboratories, anti-CALB2 antibodies are routinely applied to characterise mesothelial linings, certain classes of cortical interneurons, and adrenal cortex specimens, where calretinin expression serves as a phenotypic marker and aids differential diagnosis. The reagent is suited to immunoblotting of cell or tissue lysates and to chromogenic or fluorescent IHC on formalin-fixed paraffin-embedded sections, and it can also be adapted to immunoprecipitation protocols with standard buffer conditions.