Anti-Cadherin-19 Antibody

This rabbit polyclonal antibody from Antibodies.com targets Cadherin-19, a type II classical cadherin that mediates calcium-dependent homophilic cell-cell adhesion. The unconjugated reagent is supplied in a 100 µl vial and is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows on human samples.

Cadherin-19 (CDH19) is predominantly expressed in the central nervous system, where it contributes to neuronal migration, axon guidance, and the formation of synaptic contacts during brain development. Investigators studying neurodevelopment, neural stem cell differentiation, and cadherin-mediated adhesion signaling deploy CDH19 antibodies to map expression boundaries, identify cadherin subtype distribution in tissue sections, and characterize adherens junction dynamics. Because the target is a type II classical cadherin rather than type I, CDH19 displays a distinct adhesion partner profile and is commonly examined alongside CDH18, CDH20, and other brain-enriched cadherins.

With rabbit host, polyclonal clonality, and confirmed human reactivity, the reagent fits standard laboratory protocols: dilute for immunofluorescence on fixed cells, run Western blots under reducing conditions, apply to formalin-fixed paraffin-embedded sections for IHC, or use in ELISA plate-based detection. For handling, keep refrigerated, protect from light, and limit freeze-thaw cycles to preserve activity. Each lot is validated for the applications listed, supporting reproducible results in cell biology, developmental neuroscience, and cancer research laboratories.